Cannabinoids in Hemp

Cannabis: One Plant, Two Vibes — Hemp or Flower, It’s All Family

Here’s the truth straight from the 2018 Farm Bill: hemp and cannabis flower come from the exact same plant — Cannabis sativa L. — and the only thing separating them is a single number: 0.3% THC. That’s it. Federally, hemp is any cannabis with 0.3% or less delta-9 THC (dry weight) — fully legal to grow, process, and sell across the U.S. under USDA-approved programs. Cross that 0.3% line? Now it’s flower — still the same plant, same soil, same love — but federally classified as marijuana and subject to stricter rules. No different seeds, no different species — just one plant, two paths, defined by potency, not pedigree. At Dope Bee Farms, we celebrate both: clean, compliant hemp for wellness, and premium, high-terp flower for those who know the difference. Same roots. Same quality. Just depends on how you want to roll.

Cannabinoids: A Comprehensive Guide to the Major Compounds in Cannabis

Welcome to Dope Bee Farms' educational resource on cannabinoids—the fascinating chemical compounds produced by the cannabis plant. As a family-owned farm dedicated to sustainable cultivation, we're committed to transparency and science-backed information. This page explores the major cannabinoids, their basic properties, and how they fit into the plant's natural life cycle. Our goal is to empower you with knowledge drawn from peer-reviewed studies and expert analyses.

Important Disclaimer: The information here is for educational purposes only and does not constitute medical advice. No health claims are made about cannabinoids or cannabis products. In the opinion of our CEO, based on available scientific literature, cannabinoids offer a potentially lower-risk alternative to substances like alcohol for social and recreational use, as supported by comparative harm assessments showing reduced overall societal and individual risks [1][2][3]. Always consult a healthcare professional before incorporating any substances into your routine.

What Are Cannabinoids?

Cannabinoids are naturally occurring compounds found primarily in the Cannabis sativa plant, with over 100 identified to date [4][5]. They interact with the body's endocannabinoid system (ECS), a network of receptors (CB1 and CB2) that helps regulate various physiological processes [6][7]. The two most studied are delta-9-tetrahydrocannabinol (THC) and cannabidiol (CBD), but others like CBG, CBC, and CBN play key roles in the plant's profile [8][9].

Cannabinoids are broadly classified as:

Psychoactive: Those that can alter perception, mood, or consciousness by strongly binding to CB1 receptors in the brain (e.g., THC).
Non-Psychoactive: Those that do not produce intoxicating effects but may influence the ECS or other receptors (e.g., CBD).

Below is a table summarizing the major cannabinoids, their psychoactivity, and key characteristics based on scientific reviews.

THC Delta-9 (Δ9-Tetrahydrocannabinol)-

DESCRIPTION- Primary psychoactive compound; formed via decarboxylation of THCA. Psychoactive effects via CB1 activation; induces anandamide synthesis.

Studies- [4]

CBD (Cannabidiol)-

DESCRIPTION- Non-intoxicating; precursor CBDA. Antimicrobial properties; potential anti-psychotic modulation.

Studies- [4] [10]

CBC (Cannabichromene)-

DESRIPTION- Precursor CBCA; minor but bioactive. Anti-inflammatory in preclinical models.

Studies- [8] [13]

THCV (Tetrahydrocannabivarin)-

DESCRIPTION- THC analog; precursor THCVA. Appetite suppression in animal models.

Studies- [5] [15]

THCA (Tetrahydrocannabinolic Acid)-

DESCRIPTION- Non-psychoactive acidic precursor to THC; dominant in fresh cannabis. Anti-inflammatory and neuroprotective potential in raw form.

Studies- [39] [41]

CBG (Cannabigerol)-

DESCRIPTION- Mother cannabinoid; precursor CBGA to others. Antibacterial potential; studied for anti-inflammatory interactions.

Studies- [8] [12]

CBN (Cannabinol)-

DESCRIPTION- Degradation product of THC via oxidation. Mild psychoactivity; studied for sleep modulation.

Studies- [9] [12]

CBDV (Cannabidivarin)-

DESCRIPTION- CBD homolog; precursor CBDVA. Studied for neurological applications.

Studies- [11] [17]

[4] Cannabinoid (Wikipedia: Comprehensive overview)https://en.wikipedia.org/wiki/Cannabinoid

[5] Leafly Major Cannabinoids (includes THCV)https://www.leafly.com/news/cannabis-101/what-are-cannabinoids

[8] Major Phytocannabinoids review (PMC 2021)https://pmc.ncbi.nlm.nih.gov/articles/PMC8625816/

[9] Cannabinoids and Cannabinoid Receptors (PMC)https://pmc.ncbi.nlm.nih.gov/articles/PMC7339067/

[10] Antimicrobial / anti-psychotic modulation (Nutt harms extension + CBD studies)https://www.sciencedirect.com/science/article/abs/pii/S0955395917302573

CBD specific: https://pmc.ncbi.nlm.nih.gov/articles/PMC8625816/

[11 CBG "Mother" + TRP channels (PMC pharmacology)https://pmc.ncbi.nlm.nih.gov/articles/PMC2219532/

[12] CBG anti-inflammatory + CBN sleep (Phytocannabinoids review)https://pmc.ncbi.nlm.nih.gov/articles/PMC8625816/

[13] CBC anti-inflammatory preclinical models (PMC)https://pmc.ncbi.nlm.nih.gov/articles/PMC5627671/

[15] THCV appetite suppression animal models (PMC)https://pmc.ncbi.nlm.nih.gov/articles/PMC3671751/

[17] CBDV neurological (ASD/brain excitation PMC)https://pmc.ncbi.nlm.nih.gov/articles/PMC6868232/

[39] THCA TRP channels / raw neuroprotective (PMC) https://pmc.ncbi.nlm.nih.gov/articles/PMC10095267/

[41] THCA anti-inflammatory raw (PMC) https://pmc.ncbi.nlm.nih.gov/articles/PMC7429492/

How Cannabinoids Team Up: The “Buddy System” (Entourage Effect)

Think of cannabinoids like ingredients in your favorite smoothie — they’re good on their own, but together? Magic. Scientists call this the Entourage Effect: when THC, CBD, terpenes, and other plant compounds work as a team to create smoother, more balanced experiences. For example, CBD can take the edge off THC, so you feel relaxed instead of overwhelmed. Or myrcene (a citrusy terpene) helps THC slip into your system faster. Early lab studies show full-plant products often work better than single-compound versions — kind of like a band sounding richer than one solo singer. More human studies are coming, but the idea is simple: nature’s mix beats the lab isolate.

Why Our CEO Picks Cannabis Over Cocktails

"Look, I’m a parent. I want fun without the fallout. Science says cannabis has zero recorded overdose deaths — alcohol claims 88,000 American lives a year. It’s less linked to fights, crashes, or long-term damage. Studies rank alcohol as the #1 most harmful drug; cannabis scores way lower on risk. That’s not hype — that’s data. I’d rather spark a joint than pour a fifth, or crack open a cannabis drink instead of a IPA, which is linked to 7 cancers according to the CDC, like breast, colon, and liver cancer."

— CEO Mike, Dope Bee Farms

From Seed to Bud: The Cannabis Glow-Up (Life Cycle)

Every jar of Dope Bee flower starts as a tiny seed. Here’s how it grows — in plain normal-person-lingo:

Germination (3–10 days) – Like waking a sleepy kid. Seed pops in warm, moist soil (70–85°F). Roots down, sprout up. No cannabinoids yet — just baby steps.
Seedling (2–3 weeks) – Fragile phase! Needs 18+ hours of light. Tiny trichomes (frosty glands) start forming the first cannabinoid “building blocks” like CBGA.
Vegetative (3–16 weeks) – Growth spurt! Long sunny days = big leaves, strong stems. CBGA turns into THCA, CBDA, and others — like choosing flavors at the factory.
Flowering (8–11 weeks) – The money shot. Lights flip to 12-on/12-off. Buds swell, trichomes sparkle, cannabinoids hit peak levels (up to 30% of the bud’s weight!). THCA rules here.
Harvest & Cure – We snip at the perfect moment (trichomes go cloudy). Then slow-dry and cure to turn THCA → THC. Skip this step? You get weak, harsh flower.

We control light, water, and nutrients at every stage so your buds are balanced, potent, and clean — no guesswork.

Dive Deeper: Meet the Cannabinoids

Want the full scoop on each one? Click below:

THC – The one that lifts you up
CBD – Calm without the buzz
CBG – The “mom” of all cannabinoids
CBC – Quiet player, big potential
CBN – Your chill nighttime buddy
THCV – Energy or appetite control? You pick
CBDV – The brain-focused cousin

Last Updated: November 06, 2025